The second problem is that reference ranges are quite broad and based on the current, generally healthy population, not an optimally healthy population
For tirzepatide (Mounjaro SmPC, MHRA/EMC), arthralgia is similarly listed
The half-life is an inherent property of the medication itself, determined by its chemical structure and how your body processes it
Methylene Blue can also interact with other drugs: for example, it may increase the effects of stimulants (like amphetamines) or certain blood pressure medications, and it might reduce the effectiveness of drugs that rely on nitric oxide (like nitroglycerin)
Int J Biol Sci 13(7):852 Dooley S, Hamzavi J, Breitkopf K, Wiercinska E, Said HM, Lorenzen J, Ten Dijke P, Gressner AM (2003) Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats